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Relative IC50 values of the extracellular ECL2 peptides (Fig. 1B) for inhibition of viral entry of R5, X4, and dual tropic HIV-1 strains. Numerical values are provided in Table 1, and representative inhibition curves are shown in supplemental Fig. S1. The legend for the HIV-1 strains used is shown in the inset in each graph. A dramatic reduction in activity can be seen readily for peptides 2N, 3, and 4.
