Figure 2. Microscopic observation of cytotoxic effect of M. genitalium strains on cervical epithelial cells.
HeLa and C33A epithelial cells were infected with M. genitalium G37 and MS5 strains and analyzed using differential interference contrast at 488 nm in a confocal laser scanning microscope with 20× objective. PBS indicates uninfected control cells; G37, MGRE, MS5 and HKG37 indicate infection of cells with M. genitalium wild type G37 strain, control strain MGRE, msrA mutant strain MS5 and heat killed G37 bacteria, respectively.