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. 2012 Apr 30;7(4):e36362. doi: 10.1371/journal.pone.0036362

Figure 1. Ectopic expression of Uif* causes phenotypes that are characteristic of Notch signaling defects.

Figure 1

(A) A wt adult wing. (B and C) Targeted Uif* expression under the control of en-Gal4 causes loss of wing margin structures in the posterior wing compartment. These two panels show different expressivity, ranging from a partial loss of wing margin (arrow in B) to an almost complete loss of the posterior wing margin (black line in C). (D) A dpp-Gal4>Uif* adult wing shows wing margin loss (arrow) at the most distal tip area of the wing and an occasional loss of the anterior cross vein (arrowhead). (E and F) Thickened veins, which resemble an aspect of the Notch loss of function phenotypes (particularly veins III and V, arrows), observed in adult wings of A9-Gal4>Uif* (E) and MS1096-Gal4>Uif* (F) flies. (G–I) Expression of Uif* in the notal region causes losses of sensory bristles. (G) A wt adult notum with a regular pattern of sensory bristles. (H) The notum of Eq-Gal4>Uif* flies shows random losses of microchaeta (asterisks). (I) Expression of Uif* in the notum controlled by pnr-Gal4 leads to a great loss of sensory bristles (rectangle).