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. 2012 Apr 30;7(4):e36063. doi: 10.1371/journal.pone.0036063

Table 1. Clinicopthological data and genomic alterations in the 25 Japanese PTC cases.

Case BRAFV600E RET/PTC1 rearrangement CNA AS-UPD(CN-LOH) Percent of altered genome Age Sex Tumor size (mm) Histological type pEx pT pN M Vessel invasion Stage Recurrence
T13 + + 0.5 45 F 23 p 0 1b–m 1a 0 III
T15 + 0.0 37 F 35 p 2 4a 1a 0 I
T17 + + + 16.8 75 F 53 p+poorly 2 4a 1b M1–lung v+++ IVC +
T21 + + 1.2 63 F 23 p 1 3 x 0 III
T23 + + 2.3 62 F 38 p 2 4a 1b 0 IVA
T24 + 0.0 60 F 22 p 1 3 0 0 III
T25 + 0.0 36 F 27 p 1 3 0 0 I
T30 + 0.0 74 F 39 p 1 3 0 0 III
T45 + 0.0 69 F 36 p+poorly 1 3 1a 0 III
T53 + 0.0 60 M 20 p 1 3 1a 0 ND III
T58 + 0.0 46 F 29 p x x 1b 0 IVA
T08 + 0.0 22 F 15 p 1 3 1b 0 v+, ly+ I
T18 + 0.0 18 F 33 p 1 3 1b 0 I
T19 + + 1.8 36 F 20 p 0 1b x 0 I
T20 + 0.0 41 F 12 p 0 1b 1b 0 I
T05 + 2.0 70 F 36 p 0 2 1b 0 ND IVA
T06 + 6.0 42 F 24 fv 0 2 0 0 ND I
T07 + 2.3 46 F 8 p 1 3 x 0 ND III
T11 0.0 63 F 37 p 1 3 1a 0 ND III
T27 0.0 49 F 24 p 0 1b 1b 0 ND IVA
T32 + 1.7 56 M 45 fv 0 3 1b 0 ND IVA
T36 + 0.3 58 M 20 fv 1 3 1b 0 ND IVA
T47 0.0 68 F 20 p 0 1b 1a 0 ND III
T48 + 1.2 81 F 25 p 1 3 x 0 ND III
T50 + 3.7 56 M 65 p+poorly 1 3 1a 0 III

Using the UICC TNM classification.

Other abbreviations, F: female; M: male; p: papillary; fvp: follicular variant; ND: not described.