Table II.
Results from Granger causal connectivity analyses of the right and left hippocampus with the cortical areas involved in visceral somatosensation and emotional feeling; social cognition; and self‐related processing, during admiration for virtue (AV), compassion for social pain (CSP), admiration for skill (AS), and compassion for physical pain (CPP). Italics denote connectivity with the left hippocampus; nonitalics with the right hippocampus. Bold denotes direction of influence “toward” the hippocampus; nonbold denotes “from” the hippocampus. Talairach coordinates are in the format of x y z; negative x values correspond to the left hemisphere; coordinates are taken from regions showing Granger causal connectivity after thresholding using the false discovery rate statistic, q(FDR) < 0.01, corresponding to the following critical t‐statistics: ≥0.82 (AV), ≥1.17 (AS), ≥0.77 (CSP), and ≥0.91 (CPP)
AV | CSP | AS | CPP | |
---|---|---|---|---|
Visceral somatosensation (emotional feeling) | ||||
anterior insula | −33 16 −2, − 32 12 − 2, | −29 16 5, − 36 − 3 − 5 | ||
−31 19 −8 | ||||
anterior cingulate cortex | −1 4 35, − 2 − 3 34 | 0 16 40, 2 11 34 | ||
Social cognitive processing | ||||
temporal‐parietal junction | −47 −52 23 | |||
middle temporal gyrus | 47 −28 −3 | 48 −32 2 | −60 −22 −11 | 54 −13 −18, |
−54 −1 −20 | ||||
superior temporal sulcus | −51 −33 −3, | 52 −22 −4, | 42 11 −20 | |
57 − 28 − 3 | −53 0 −8 | |||
superior temporal gyrus | 48 − 19 13 | −51 −30 13, | ||
−55 −44 4, | 48 −13 3 | |||
−53 −1 19 | ||||
temporal pole | −52 2 −1 | |||
ventromedial PFC | −1 41 −5 | −3 47 −5 | −9 41 −8, | |
15 38 −5 | ||||
ventrolateral PFC | −28 13 −10, −33 37 0 | −29 24 −7 | ||
29 43 0 | ||||
Self‐related processing | ||||
posteromedial cortices: | ||||
posterior cingulate | 3 −34 31, 3 − 39 31 | 0 −41 31 | ||
retrosplenium | 0 −38 23,−6 −53 16 | |||
precuneus | 4 −40 40, 7 −61 44; | 2 −62 33 | −1 −61 46 | |
6 − 49 60, 9 − 52 35 | −3 −51 31, | |||
−2 −47 46, 0 | ||||
−57 32, 1 − 67 44 | ||||
dorsomedial PFC | ||||
− 1 42 31 | −3 51 9 |