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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Am J Obstet Gynecol. 2012 Feb 22;206(5):448.e1–448.e7. doi: 10.1016/j.ajog.2012.02.011

Figure 1.

Figure 1

Copper zinc superoxide dismutase 1 (SOD1) treatment blocks high glucose-induced iNOS expression. In A, SOD1 dose-dependently suppressed high glucose-induced iNOS-luciferase activities, which were normalized by Renilla-luciferase activities and expressed as iNOS/Renilla. * indicates significant difference (p < 0.05) when compared to the high glucose (450 mg/dL or 25 mM) alone group. n = 5. In B, SOD1 treatment suppressed high glucose-increased iNOS protein expression. Representative images were shown in the upper panel and the data of densitometric analysis were presented in the bottom graph. * indicates significant difference (p < 0.05) when compared to other groups. n = 3 (three independent experiments).