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. 2012 Apr 25;7(4):e35792. doi: 10.1371/journal.pone.0035792

Figure 6. Structure-based pharmacophore for IspE inhibitors considering the possible tautomers of His25.

Figure 6

Either ND (a) or NE (b) are carrying the hydrogen atom. Hydrogen-bond donor features and their corresponding binding partners in the protein are shown in purple and hydrogen-bond acceptor features and their corresponding binding partners are coloured green.