Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The mesh represents the combined van der Waals radii of the ligand atoms. In this orientation the pyridinyl group is stacked between Tyr24 and Tyr175 and forms hydrogen bonds with His25. Further, the hydroxyl group forms a hydrogen bond with Asp130 while the indolyl moiety is buried in a hydrophobic cleft.
