Table 2. Physico-chemical properties, inhibition values, and ligand efficiencies for in vitro screening hits.

ID	MW [g/mol]	clogP	IC50 [M] (SD)*	Hill slope (SD)*	Ligand efficiency [kcal/mol per non-hydrogen atom]
7	329	3.63	1.9·10−5 (2·10−6)	1.4 (0.1)	0.29
8	379	2.79	2.5·10−6 (4·10−7)	1.3 (0.1)	0.35

For chemical structures see Figure 9.

^*average values of three independent measurements, standard deviation in brackets.