Table 3. Hit expansion for ligand 3.

ID	IC50 [M] (SD)*	Hill slope (SD)*	Ligand efficiency [kcal/mol per non-hydrogen atom]
3	1.6·10−4 (9·10−6)	1.0 (0.1)	0.50
9	9.4·10−3 (2·10−3)	1.4 (0.0)	0.30
10	6.6·10−3 (2·10−4)	1.1 (0.2)	0.27
11	2.0·10−3 (4·10−4)	1.1 (0.4)	0.50

For chemical structures see Figure 11.

^*average values of three independent measurements, standard deviation in brackets.