Table 5. Hit expansion for ligand 7.

ID	IC50 [M] (SD)*	Hill slope (SD)*	Ligand efficiency [kcal/mol per non-hydrogen atom]
7	1.9·10−5 (2·10−6)	1.4 (0.1)	0.29
18	5.5·10−4 (5·10−8)	0.8 (0.0)	0.21
19	2.4·10−3 (4·10−4)	0.8 (0.1)	0.18
20	2.5·10−3 (3·10−4)	1.1 (0.1)	0.18

For chemical structures see Figure 14.

^*average values of three independent measurements, standard deviation in brackets.