Fig. 6.

L-755,507 (100 μM) significantly reduced carbachol-induced phasic and tonic contractions of DSM isolated strips. A: original DSM contraction recording illustrating L-755,507 (100 μM) inhibitory effect in the absence of SR59230A (10 μM). B: summary data showing that L-755,507 (100 μM) significantly reduced the amplitude, muscle force integral, phasic contraction duration, and muscle tone (n = 12, N = 3, *P < 0.05, **P < 0.01, ***P < 0.005). TTX (1 μM) was present throughout the experiments.