Table 2.
Significant activations for intra- and inter-group comparisons for the (stem-cued recall – stem-completion) contrast (p < 0.005 uncorrected, cluster extent > 50 voxels).
| Cluster extent | Anatomical region (BA) | H | Peak coordinates |
Z-score | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| AD PATIENTS | ||||||
| 413 | Posterior cingulate cortex (31) | B | 0 | −40 | 42 | 4.43 |
| 231 | Supramarginal gyrus (40) | R | 62 | −50 | 28 | 4.53 |
| 215 | Middle frontal gyrus (10) | R | 34 | 58 | 2 | 3.81 |
| Superior frontal gyrus (10) | R | 26 | 64 | −10 | 2.96 | |
| 154 | Superior frontal gyrus (8) | R | 20 | 22 | 50 | 3.68 |
| 56 | Middle frontal gyrus (11) | R | 44 | 52 | −10 | 3.23 |
| NORMAL CONTROLS | ||||||
| 1278 | Middle frontal gyrus (10) | R | 38 | 54 | 18 | 5.32 |
| Superior frontal gyrus (10) | R | 30 | 64 | 4 | 4.25 | |
| 26 | 54 | 4 | 4.16 | |||
| 801 | Cerebellum | L | −34 | −84 | −20 | 4.65 |
| −32 | −70 | −14 | 3.84 | |||
| −42 | −60 | −34 | 3.5 | |||
| 305 | Inferior parietal lobule (40) | R | 52 | −62 | 38 | 4.05 |
| 202 | Inferior frontal gyrus (47) | R | 36 | 22 | −18 | 3.36 |
| Insula (47) | R | 36 | 22 | −6 | 3.3 | |
| 130 | Parahippocampal gyrus (28) | L | −26 | 2 | −28 | 3.44 |
| 118 | Inferior parietal lobule (40) | L | −30 | −52 | 38 | 3.58 |
| 103 | Superior frontal gyrus (11) | R | 20 | 54 | −20 | 3.62 |
| 81 | Supramarginal gyrus (40) | L | −62 | −54 | 30 | 3.96 |
| 74 | Middle frontal gyrus (9) | R | 48 | 12 | 40 | 3.47 |
| 67 | Cuneus (18) | R | 14 | −74 | 28 | 3.17 |
| 63 | Hippocampus | R | 30 | −8 | −26 | 3.38 |
| NORMAL CONTROLS > AD PATIENTS | ||||||
| 347 | Parahippocampal gyrus (28) | L | −24 | 0 | −30 | 3.91 |
| −32 | 10 | −18 | 2.69 | |||
| 332 | Inferior occipital gyrus (18) | L | −34 | −86 | −20 | 3.58 |
| Lingual gyrus (18) | L | −34 | −70 | −14 | 3.39 | |
| Cerebellum | L | −38 | −84 | −34 | 2.82 | |
| 177 | Inferior parietal lobule (40) | L | −28 | −52 | 36 | 4.27 |
| Supramarginal gyrus (40) | L | −36 | −48 | 32 | 4.19 | |
| Superior temporal gyrus (13) | L | −40 | −48 | 20 | 3.2 | |
| 125 | Superior frontal gyrus (10) | R | 38 | 52 | 22 | 3.72 |
| Middle frontal gyrus (10) | R | 34 | 60 | 16 | 3.27 | |
| 78 | Cerebellum | R | 4 | −50 | −20 | 3.57 |
| 61 | Middle occipital gyrus (39) | R | 48 | −78 | 12 | 3.54 |
| AD PATIENTS > NORMAL CONTROLS | ||||||
| 238 | Middle cingulate cortex (31) | R | 10 | −24 | 48 | 4.42 |
| Precentral gyrus (6) | R | 14 | −20 | 68 | 3.69 | |
| 68 | Precuneus (7) | L | −2 | −46 | 50 | 3.51 |
| 51 | Precuneus (7) | R | 2 | −50 | 52 | 3.59 |
| CONJUNCTION | ||||||
| 124 | Middle frontal gyrus (10) | R | 32 | 58 | 4 | 3.44 |
Coordinates are in MNI space. BA, Brodmann area; H, hemisphere; B, bilateral; L, left; R, right.