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Secretagogin+ neurons in the olfactory tract are lost in AD. (A–A1″) Secretagogin+ neurons (open arrowheads) can exhibit neurofibrillary tangle pathology (AT8+) (filled arrowheads) in the human olfactory tract. (B and B1) Age (R2 = 0.62, P < 0.01) and Alzheimer's stage-related decline of secretagogin+ shell cells in the olfactory tract. *P < 0.05. [Scale bars: 20 μm (A) and 10 μm (A1″).]
