Fig. 4.

Effect of Plfgyr EGS-based CPP-MO on P. falciparum development and egress. Parasite intraerythrocytic development was assessed in the absence or presence of 2 μM of the CPP-MO used in Fig. 1B after 8, 16, 24, 32, and 40 h following merozoite invasion. (A) Morphology of parasites during the course of the assay. (B–D) Percentage of each parasite developmental stage 40 h (B), 48 h (C), and 56 h (D) after merozoite invasion. (E) Images of abnormal schizonts unable to rupture 56 h postmerozoite invasion.