Table 2.
SNP | Gene | P values | |||
---|---|---|---|---|---|
BIF | CCA | ICA | Total | ||
Chromosome 7 | |||||
rs3815483 | ANLN | 0.00023 | 0.08852 | 0.11102 | 0.00360 |
rs2001600 | AOAH | 0.00092 | 0.02931 | 0.22562 | 0.00422 |
Chromosome 14 | |||||
rs1667498 | 0 | 0.00679 | 0.04423 | 0.00627 | 0.00062 |
rs10144627 | FOXN3 | 0.00131 | 0.00864 | 0.00088 | 0.00023 |
rs10151997 | FOXN3 | 0.00160 | 0.00638 | 0.03823 | 0.00059 |
rs10151430 | FOXN3 | 0.00547 | 0.02747 | 0.00764 | 0.00089 |
rs17803546 | CCDC88C | 0.02980 | 0.00369 | 0.00216 | 0.00056 |
rs7152362 | PRIMA1 | 0.00262 | 0.00187 | 0.09807 | 0.00007 |
Each SNP was tested for association with maximum IMT at bifurcation (BIF), common carotid artery (CCA), internal carotid artery (ICA), and a mean composite measure of the IMT of all three carotid sites (Total). P values from the QTDT test in the 100 DR families are reported in the table.