Figure 1.

(A) Mean densitometry of protein levels of phosphorylated insulin receptor were significantly increased in Müller cells after treatment with the β-adrenergic receptor agonist isoproterenol. (B) Mean densitometry showing the ratio of Akt to phosphorylated Akt. Protein levels of Akt were significantly increased in Müller cells cultured in high-glucose (25 mM glucose) medium after treatment with 10 μM isoproterenol. Significance was determined by one-tailed, nonparametric t-tests on Western blot data. (A) *P < 0.05 vs. untreated, n = 4; (B) *P < 0.05 vs. untreated, n = 4.