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. 2012 Mar 12;30(12):1280–1287. doi: 10.1200/JCO.2011.36.4109

Table 5.

Odds Ratios for Having High-Risk CRP Level

ω-6:ω-3 Ratio Tertile and Supplement Use Odds Ratio 95% CI
Model 1*
    Lowest, nonusers v lowest, users 3.1 1.3 to 7.4
    Middle, users v lowest, users 1.8 0.6 to 5.6
    Middle, nonusers v lowest, users 3.6 1.5 to 8.7
    Highest, users v lowest, users 2.4 0.6 to 5.6
    Highest, nonusers v lowest, users 4.6 1.9 to 11.0
Model 2
    Lowest, nonusers v lowest, users 2.7 1.1 to 6.5
    Middle, users v lowest, users 1.8 0.5 to 5.6
    Middle, nonusers v lowest, users 2.9 1.2 to 7.1
    Highest, users v lowest, users 2.2 0.6 to 9.0
    Highest, nonusers v lowest, users 3.8§ 1.6 to 9.3
Model 3
    Lowest, nonusers v lowest, users 3.2 1.2 to 8.4
    Middle, users v lowest, users 1.8 0.5 to 6.5
    Middle, nonusers v lowest, users 3.3 1.3 to 8.6
    Highest, users v lowest, users 2.6 0.6 to 11.4
    Highest, nonusers v lowest, users 4.5§ 1.7 to 11.5

Abbreviation: CRP, C-reactive protein.

*

Model 1 adjusts for age, race/study site, tamoxifen use, and menopausal status.

P < .01 comparing odds ratios for being fatigued across subgroups determined by ω-6:ω-3 ratio tertile and supplement use.

Model 2 adjusts for model 1 plus antidepressant/anxiolytic use and number of comorbidities.

§

P < .05 comparing odds ratios for being fatigued across subgroups determined by ω-6:ω-3 ratio tertile and supplement use.

Model 3 adjusts for model 2 plus body mass index.