Table 1.
Patient Demographics and Clinical Characteristics by Cohort
| Demographic or Clinical Characteristic | Colon Cancer |
Rectal Cancer |
NSCLC |
Small-Cell Lung Cancer |
Non-Hodgkin's Lymphoma |
Multiple Myeloma |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| VHA | SEER-Medicare | VHA | SEER-Medicare | VHA | SEER-Medicare | VHA | SEER-Medicare | VHA | SEER-Medicare | VHA | SEER-Medicare | |
| N | 7,003 | 20,734 | 1,757 | 4,562 | 13,434 | 31,868 | 2,111 | 4,669 | 613 | 3,192 | 900 | 3,170 |
| Age, % | ||||||||||||
| 66-69 years | 17.8 | 15.0 | 18.1 | 17.8 | 21.9 | 18.3 | 24.4 | 21.2 | 16.0 | 14.4 | 18.6 | 16.9 |
| 70-74 years | 28.0 | 23.3 | 30.4 | 25.6 | 30.5 | 27.3 | 32.6 | 28.7 | 24.6 | 22.6 | 25.0 | 24.8 |
| 75-79 years | 28.5 | 25.2 | 28.1 | 25.3 | 29.2 | 26.9 | 27.6 | 28.0 | 29.2 | 25.9 | 28.4 | 25.5 |
| 80-84 years | 19.2 | 20.9 | 18.5 | 18.5 | 15.0 | 18.0 | 12.4 | 15.1 | 23.0 | 22.7 | 23.1 | 19.6 |
| ≥ 85 years | 6.5 | 15.7 | 5.0 | 12.8 | 3.4 | 9.6 | 3.0 | 7.1 | 7.2 | 14.4 | 4.9 | 13.2 |
| Race, % | ||||||||||||
| White | 78.3 | 90.3 | 80.8 | 92.0 | 80.7 | 89.4 | 85.1 | 91.7 | 88.8 | 94.4 | 64.7 | 82.9 |
| African American | 16.3 | 8.1 | 13.7 | 6.0 | 17.2 | 9.1 | 12.6 | 6.9 | 6.2 | 3.3 | 27.8 | 14.6 |
| Hispanic | 5.4 | 1.5 | 5.5 | 2.0 | 2.2 | 1.5 | 2.3 | 1.4 | 5.0 | 2.3 | 6.5 | 2.4 |
| Missing | 2.1 | 4.9 | 2.3 | 5.6 | 1.5 | 4.7 | 1.5 | 4.0 | 2.4 | 5.0 | 2.1 | 3.2 |
| Marital status, % | ||||||||||||
| Single | 44.0 | 29.4 | 44.8 | 29.4 | 47.7 | 31.9 | 46.9 | 30.8 | 43.4 | 24.9 | 39.0 | 26.5 |
| Married | 56.0 | 70.6 | 55.2 | 70.6 | 52.3 | 68.1 | 53.1 | 69.3 | 56.6 | 75.2 | 61.0 | 73.5 |
| Missing | 2.6 | 3.1 | 2.5 | 3.4 | 2.3 | 2.6 | 1.8 | 2.3 | 1.1 | 3.1 | 1.9 | 4.9 |
| Census region, % | ||||||||||||
| Northeast | 17.1 | 25.1 | 15.9 | 24.6 | 14.6 | 22.1 | 13.8 | 20.5 | 13.5 | 23.5 | 14.6 | 22.6 |
| Midwest | 20.0 | 15.8 | 21.1 | 15.4 | 21.3 | 15.8 | 24.8 | 17.3 | 21.5 | 15.7 | 21.8 | 17.6 |
| South | 46.2 | 19.2 | 45.7 | 18.8 | 46.9 | 23.5 | 43.9 | 25.7 | 42.6 | 16.5 | 43.7 | 19.2 |
| West | 16.7 | 39.9 | 17.3 | 41.3 | 17.2 | 38.6 | 17.5 | 36.5 | 22.4 | 44.2 | 20.0 | 40.7 |
| Socioeconomic variables* | ||||||||||||
| With college degree in zip code of residence, % | 25.6 | 31.7 | 24.6 | 30.8 | 24.6 | 29.7 | 24.6 | 28.8 | 27.6 | 34.2 | 26.8 | 32.4 |
| Professionals in zip code of residence, % | 29.5 | 34.3 | 28.8 | 33.6 | 28.9 | 32.9 | 28.8 | 32.1 | 31.0 | 36.1 | 30.4 | 34.9 |
| Median household income in zip code of residence, $ | 44,800 | 56,500 | 44,400 | 55,500 | 44,500 | 54,000 | 45,200 | 53,000 | 47,300 | 59,600 | 45,300 | 57,300 |
| Age ≥ 65 years with income < poverty level in zip code of residence, % | 12.5 | 9.2 | 12.3 | 9.2 | 12.2 | 9.7 | 11.5 | 9.8 | 11.2 | 8.4 | 13.0 | 9.4 |
| Hispanic in zip code of residence, % | 12.2 | 11.7 | 12.9 | 12.5 | 10.3 | 11.6 | 10.0 | 11.5 | 11.7 | 11.5 | 13.0 | 11.7 |
| African American in zip code of residence, % | 16.1 | 10.1 | 14.0 | 9.1 | 16.8 | 10.7 | 14.0 | 9.8 | 10.6 | 7.3 | 20.2 | 12.3 |
| Missing census data, % | 5.7 | 2.9 | 4.7 | 2.9 | 4.6 | 2.9 | 4.7 | 2.6 | 4.6 | 2.7 | 6.7 | 2.8 |
| Charlson comorbidity score, % | ||||||||||||
| 0 | 44.4 | 49.0 | 51.0 | 57.1 | 54.1 | 56.9 | 53.0 | 55.2 | 41.3 | 50.0 | 40.1 | 47.5 |
| 1 | 30.8 | 26.6 | 29.7 | 25.0 | 25.8 | 24.4 | 25.3 | 24.9 | 31.5 | 25.8 | 25.4 | 23.2 |
| 2 | 14.1 | 13.4 | 11.0 | 10.0 | 12.2 | 10.8 | 12.4 | 10.8 | 14.7 | 13.0 | 17.2 | 14.2 |
| ≥ 3 | 10.7 | 11.0 | 8.3 | 8.0 | 7.9 | 8.0 | 9.3 | 9.1 | 12.6 | 11.2 | 17.2 | 15.1 |
| COPD, % | 45.0 | 41.8 | 44.5 | 42.9 | ||||||||
| Prior cancer, % | 16.7 | 23.5 | 16.1 | 23.3 | 21.3 | 25.9 | 19.2 | 21.7 | 19.3 | 25.9 | 20.0 | 24.3 |
| Tumor grade, % | ||||||||||||
| Well differentiated | 11.9 | 10.4 | 10.4 | 9.3 | 6.6 | 6.7 | ||||||
| Moderately differentiated | 72.9 | 70.5 | 75.5 | 73.7 | 33.4 | 30.4 | ||||||
| Undifferentiated | 15.3 | 19.2 | 14.1 | 17.1 | 60.1 | 63.0 | ||||||
| Tumor grade missing, % | 13.9 | 10.1 | 18.2 | 13.3 | 50.8 | 48.7 | ||||||
| Stage at diagnosis, % | ||||||||||||
| I | 31.7 | 26.4 | 38.3 | 39.7 | 28.0 | 23.4 | 23.8§ | 33.1§ | ||||
| II | 28.1 | 31.2 | 26.9 | 23.3 | 7.1 | 5.6 | 39.7† | 37.7† | 12.2§ | 17.7§ | ||
| III | 22.7 | 24.7 | 19.9 | 22.1 | 26.5 | 29.5 | 23.2§ | 15.9§ | ||||
| IV | 17.5 | 17.6 | 14.9 | 14.9 | 38.4 | 41.6 | 60.3‡ | 62.3‡ | 40.9§ | 33.3§ | ||
| Stage missing, % | 7.7 | 5.0 | 11.6 | 9.4 | 5.2 | 9.0 | 4.6 | 6.8 | 9.9§ | 8.5§ | ||
| Tumor size, %¶ | ||||||||||||
| T1 | 22.3 | 17.6 | 24.8 | 23.9 | 25.1 | 21.8 | ||||||
| T2 | 20.1 | 17.2 | 23.7 | 25.3 | 38.4 | 35.4 | ||||||
| T3 | 51.2 | 54.7 | 45.7 | 45.5 | 12.1 | 9.2 | ||||||
| T4 | 6.5 | 10.5 | 5.8 | 5.3 | 24.5 | 33.7 | ||||||
| Tumor size missing, %¶ | 1.2 | 1.9 | 2.4 | 5.5 | 12.3 | 10.1 | ||||||
Abbreviations: COPD, chronic obstructive pulmonary disease; NSCLC, non–small-cell lung cancer; SEER, Surveillance, Epidemiology, and End Results; VHA, Veterans Health Administration.
*
Obtained from 2000 Census by linking to the zip code of the residence of the patient.
†
Limited stage.
‡
Extensive stage.
§
Stage collected in 2004 only.
¶
Among stage I/II/III cancers.