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Antagonism of LFA-1-dependent T lymphocyte adhesion in vivo. (A) Homing to PLNs. Data are expressed as mean ± SEM (n = 3). *, P < 0.05 vs. wild type. (B and C) Effect of I domains on T lymphocyte rolling and sticking in high endothelial venules of subiliac PLN. Data are mean ± SEM (a total of 15 vessels in four mice were analyzed). **, P < 0.01 vs. control or wild type.
