Table 1. Characteristics of the participants in the CGPS, CCHS, and CIHDS by BMI tertile.
| Characteristics | CGPS | CCHS | CIHDS | ||||||||||
| Tertile 1 | Tertile 2 | Tertile 3 | Overall | Tertile 1 | Tertile 2 | Tertile 3 | Overall | Tertile 1 Controls | Tertile 2 Controls | Tertile 3 Controls | Controls | Overall | |
| n | 18,063 | 18,060 | 18,060 | 54,613 | 3,488 | 3,488 | 3,488 | 10,474 | 1,758 | 1,756 | 1,756 | 5,270 | 10,540 |
| BMI (kg/m2) | 22.3 (21.1–23.2) | 25.6 (24.8–26.4) | 29.9 (28.5–32.3) | 25.6 (23.2–28.5) | 21.0 (20.0–21.8) | 23.9 (23.3–24.7) | 27.9 (26.7–30.0) | 23.9 (21.8–26.7) | 22.2 (21.1–23.2) | 25.4 (24.6–26.2) | 29.5 (28.1–31.8) | 25.4 (23.2–28.1) | 25.5 (23.3–28.1) |
| Waist hip ratio | 0.81 (0.77–0.87) | 0.88 (0.82–0.93) | 0.93 (0.86–0.98) | 0.87 (0.81–0.93) | 0.81 (0.76–0.87) | 0.87 (0.81–0.93) | 0.93 (0.86–0.99) | 0.87 (0.80–0.94) | 0.81 (0.77–0.87) | 0.87 (0.82–0.92) | 0.92 (0.86–0.97) | 0.87 (0.80–0.93) | 0.87 (0.80–0.93) |
| Women (%) | 70.3 | 48.4 | 47.7 | 55.6 | 70.6 | 51.8 | 44.3 | 55.6 | 72.8 | 49.8 | 47.3 | 56.6 | 43.0 |
| Age (y) | 54 (44–65) | 58 (48–67) | 60 (50–68) | 57 (47–67) | 54 (40–67) | 60 (48–70) | 64 (54–72) | 60 (47–70) | 54 (45–64) | 56 (46–66) | 59 (49–69) | 56 (46–66) | 60 (51–69) |
| Ever smoked (%) | 56.4 | 60.7 | 61.3 | 59.3 | 58.0 | 56.0 | 53.2 | 55.7 | 56.5 | 59.7 | 60.5 | 58.9 | 59.5 |
| Drinking (%) | 73.4 | 75.2 | 68.5 | 72.1 | 50.9 | 56.0 | 53.3 | 53.4 | 74.6 | 75.5 | 69.5 | 73.2 | 59.4 |
| Education (%)a | 20.3 | 27.2 | 37.6 | 28.4 | 38.2 | 50.8 | 66.0 | 51.6 | 20.1 | 27.5 | 36.1 | 27.9 | 27.9 |
| Education (%)b | 58.0 | 55.5 | 48.9 | 54.1 | 46.1 | 36.8 | 27.9 | 36.9 | 58.3 | 55.7 | 50.1 | 54.7 | 54.7 |
| Education (%)c | 21.8 | 17.3 | 13.5 | 17.5 | 15.8 | 12.4 | 6.1 | 11.4 | 21.6 | 16.8 | 13.8 | 17.4 | 17.4 |
| Income (%)d | 2.0 | 1.6 | 2.1 | 1.9 | 19.9 | 16.4 | 18.1 | 18.1 | 2.7 | 1.4 | 1.9 | 2.0 | 2.0 |
| Income (%)e | 35.4 | 36.2 | 43.9 | 38.6 | 52.5 | 53.9 | 56.4 | 54.3 | 35.8 | 35.9 | 41.6 | 37.7 | 37.7 |
| Income (%)f | 38.8 | 40.7 | 38.9 | 39.4 | 24.3 | 26.0 | 22.9 | 24.4 | 37.8 | 41.9 | 41.0 | 40.3 | 40.3 |
| Income (%)g | 23.8 | 21.5 | 15.1 | 20.1 | 3.3 | 3.7 | 2.7 | 3.2 | 23.7 | 20.8 | 15.5 | 20.0 | 20.0 |
| IHD (%) | 4.3 | 6.9 | 9.6 | 6.9 | 12.4 | 17.8 | 27.3 | 19.2 | NA | NA | NA | NA | 50.0 |
| Event time (y) | 2.1 (1.2–3.6) | 2.3 (1.1–3.7) | 2.4 (1.0–3.7) | 2.3 (1.1–3.7) | 15.6 (11.8–16.5) | 15.3 (9.3–16.2) | 13.5 (6.5–15.9) | 15.2 (8.7–16.2) | 2.5 (1.5–3.9) | 2.6 (1.3–3.9) | 2.6 (1.2–3.9) | 2.6 (1.3–3.9) | NA |
| SBP (mmHg) | 132 (120–148) | 140 (126–154) | 145 (132–160) | 140 (125–155) | 120 (111–132) | 127 (117–139) | 134 (123–147) | 127 (116–140) | 130 (120–145) | 140 (125–155) | 145 (132–160) | 140 (125–154) | 140 (125–154) |
| DBP (mmHg) | 80 (72–86) | 82 (75–90) | 86 (80–95) | 82 (75–90) | 75 (69–83) | 80 (73–87) | 85 (78–93) | 80 (72–88) | 80 (72–86) | 83 (76–90) | 87 (80–95) | 83 (75–90) | 81 (75–90) |
| Hypertension (%) | 56.5 | 70.2 | 83.0 | 70.0 | 19.2 | 32.1 | 51.1 | 34.2 | 54.4 | 67.8 | 81.7 | 68.0 | 52.7 |
| AH medicine (%) | 11.3 | 17.8 | 28.3 | 19.1 | 1.8 | 2.4 | 6.0 | 3.4 | 10.9 | 13.8 | 24.5 | 16.4 | 23.6 |
| Adjusted SBP (mmHg) | 132 (120–150) | 140 (128–156) | 149 (135–164) | 140 (126–157) | 120 (111–132) | 128 (117–140) | 135 (123–148) | 127 (116–140) | 131 (120–148) | 140 (125–156) | 147 (134–162) | 140 (125–156) | 140 (126–158) |
| Adjusted DBP (mmHg) | 80 (72–87) | 84 (76–90) | 88 (80–95) | 84 (76–91) | 75 (69–83) | 80 (73–87) | 85 (78–93) | 80 (73–88) | 84 (76–92) | 80 (73–87) | 84 (76–91) | 84 (76–92) | 83 (75–91) |
| Glucose (mmol/l) | 5.0 (4.6–5.5) | 5.1 (4.7–5.6) | 5.2 (4.8–5.8) | 5.1 (4.7–5.6) | 5.7 (5.1–6.3) | 5.9 (5.3–6.5) | 6.1 (5.6–6.8) | 5.9 (5.3–6.6) | 5.0 (4.6–5.5) | 5.0 (4.7–5.5) | 5.2 (4.8–5.8) | 5.1 (4.7–5.6) | 5.1 (4.7–5.6) |
| LDL cholesterol (mmol/l) | 3.0 (2.4–3.6) | 3.2 (2.6,3.9) | 3.4 (2.7–4.0) | 3.2 (2.6–3.9) | 3.3 (2.6–4.2) | 3.6 (2.9–4.4) | 3.8 (3.1–4.6) | 3.6 (2.9–4.4) | 3.0 (2.4–3.6) | 3.2 (2.7–3.9) | 3.4 (2.8–4.0) | 3.2 (2.6–3.9) | 3.1 (2.4–3.8) |
| HDL cholesterol (mmol/l) | 1.8 (1.5–2.2) | 1.6 (1.3–1.9) | 1.4 (1.1–1.7) | 1.6 (1.3–1.9) | 1.6 (1.3–1.9) | 1.5 (1.2–1.7) | 1.3 (1.1–1.6) | 1.5 (1.2–1.7) | 1.8 (1.5–2.2) | 1.6 (1.3–1.9) | 1.4 (1.1–1.7) | 1.6 (1.3–2.0) | 1.4 (1.1–1.8) |
| Triglycerides (mmol/l) | 1.1 (0.8–1.5) | 1.4 (1.0–2.1) | 1.8 (1.3–2.6) | 1.4 (1.0–2.1) | 1.1 (0.8–1.5) | 1.3 (0.9–1.8) | 1.7 (1.2–2.5) | 1.3 (0.9–1.9) | 1.1 (0.8–1.5) | 1.4 (1.0–2.1) | 1.8 (1.3–2.6) | 1.4 (1.0–2.1) | 1.5 (1.0–2.2) |
Data are from study enrolment in 2003–2009 in the CGPS, from the 1991–1994 or 2001–2003 examinations of the CCHS when DNA was collected, and from study enrolment in 1991–2009 in the CIDHS. Values are median and interquartile range or number of participants and percentages. Drinking alcohol represented by <14/21; ≥14/21 units per week for women/men at the time of examination. Event time is the absolute value of the difference between age at IHD event and age at measurement of BMI (y). SBP and DBP adjusted by adding 10 and 5 mmHg to each, respectively, if patient on AH medication. To convert glucose values in mmol/l to mg/dl, multiply by 18. To convert LDL and HDL cholesterol values in mmol/l to mg/dl, multiply by 38.6. To convert triglyceride values in mmol/l to mg/dl, multiply by 88. In CIHDS, education and income are only available in controls.
<10 y of schooling.
≥10 to <13 y of schooling.
≥13 y of schooling.
<100,000DKK annual income.
100,000DKK–400,000DKK annual income.
400,000–600,000DKK annual income.
>600,000DKK annual income.
AH, antihypertensive; DBP, diastolic blood pressure; HDL, high density lipoprotein; LDL, low density lipoprotein; SBP, systolic blood pressure.