Table 2. Distribution of FTO, MC4R, and TMEM18 genotypes in the CGPS, CCHS, and CIHDS.
| Genotype or Allele Score | 0 | 1 | 2 | 3 | 4 | 5 | 6 |
| Genotype | |||||||
| CPGS | |||||||
| FTO(rs9939609), n (%) | 17,846 (35.2) | 24,595 (48.5) | 8,307 (16.4) | ||||
| MC4R(rs17782313), n (%) | 28,797 (56.7) | 18,862 (37.2) | 3,092 (6.1) | ||||
| TMEM18(rs6548238), n (%) | 1,517 (2.9) | 15,036 (28.4) | 36,435 (68.9) | ||||
| CCHS | |||||||
| FTO(rs9939609), n (%) | 3,744 (35.8) | 4,981 (47.6) | 1,748 (16.7) | ||||
| MC4R(rs17782313), n (%) | 5,998 (57.3) | 3,841 (36.7) | 635 (6.1) | ||||
| TMEM18(rs6548238), n (%) | 316 (3.0) | 2,975 (28.4) | 7,180 (68.6) | ||||
| CIHDS | |||||||
| FTO(rs9939609), n (%) | 3,613 (34.3) | 5,159 (49.0) | 1,768 (16.8) | ||||
| MC4R(rs17782313), n (%) | 5,913 (56.1) | 3,930 (37.3) | 697 (6.6) | ||||
| TMEM18(rs6548238), n (%) | 279 (2.7) | 2,955 (28.0) | 7,306 (69.3) | ||||
| Allele score | |||||||
| CPGS, n (%) | 58 (0.6) | 738 (7.1) | 2,782 (26.6) | 3,768 (36.0) | 2,386 (22.8) | 658 (6.3) | 80 (0.8) |
| CCHS, n (%) | 294 (0.6) | 3,452 (6.8) | 13,203 (26.0) | 18,578 (36.6) | 11,556 (22.8) | 3,283 (6.5) | 349 (0.7) |
| CIHDS, n (%) | 55 (0.5) | 682 (6.5) | 2,672 (25.4) | 3,831 (36.4) | 2,506 (23.8) | 721 (6.8) | 73 (0.7) |
All SNPs adhere to Hardy-Weinberg Equilibrium (p>0.2). FTO(rs9939609) genotypes, 0 (TT), 1 (AT), 2 (AA); MC4R(rs17782313) genotypes 0 (TT), 1 (CT), 2 (CC); TMEM18(rs6548238) genotypes 0 (TT), 1 (CT), 2 (CC). Allele score constructed from the following genotypes: FTO(rs9939609), 0 (TT), 1 (AT), 2 (AA); MC4R(rs17782313), 0 (TT), 1 (CT), 2 (CC); TMEM18(rs6548238), 0 (TT), 1 (CT), 2 (CC).