Figure 3. Effects of nebulized CK-165 on hypoxia induced pulmonary hypertension.

The efficacy of nebulized CK-165 (4 mg/kg) and nitroprusside (2 µg/kg) were examined and compared in the porcine hypoxia model of pulmonary hypertension. All changes were plotted as percent change from baseline. When delivered continuously, similar effect profiles are observed between CK-165 and nitroprusside.