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. 2012 May 1;7(5):e36188. doi: 10.1371/journal.pone.0036188

Figure 10.

Figure 10

A) Ultrastructural morphometric analysis of beta-cell death in human islets after 48 h exposure to 0.5 mM palmitic acid ±10 ng/ml rapamycin. C = control; P = 0.5 mM palmitic acid; P+R = 0.5 mM palmitic acid plus 10 ng/ml rapamycin. Mean of 3–4 samples ± SEM. Statistical analysis (Bonferroni's test): * p<0.05 vs control and vs palmitate+rapamycin; # p>0.05 vs palmitate. B) Electron microscopy of isolated human islets in control conditions (left) and after 48 h incubation with 0.5 mM PA (center) or 0.5 mM PA+10 ng/ml rapamycin (right). (magnification: 10.000×).