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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Free Radic Biol Med. 2012 Feb 25;52(9):1744–1749. doi: 10.1016/j.freeradbiomed.2012.02.021

Fig. 1.

Fig. 1

CEdG concentration after incubation of DNA under oxidative conditions at 37°C for 14 d: (A) herring sperm DNA (1 mg/mL) in the presence of air oxygen, hydrogen peroxide (H2O2, 1 mM), or xanthine oxidase/xanthine (XO-X, 25 mU/mL/0.4 mM); (B) DNA, DNA/H2O2 and DNA/H2O2 incubated in the presence of D-glucose (Gluc, 5 mM); (C) DNA/XO-X in absence and presence of catalase (CAT) or superoxide dismutase and catalase (SOD/CAT);(D) DNA and DNA/H2O2 in the absence and presence of pyridoxamine (PM, 10 mM). Concentrations are given as ng CEdG/mL incubation mixture. Data from each time point was measured in triplicates. Mean and standard deviation are shown. Significant differences between DNA and DNA/H2O2 or DNA/XO-X (A), between DNA/XO-X and DNA/XO-X/SOD/CAT or DNA/XO-X/CAT (C), between DNA/H2O2 and DNA/H2O2/PM (D) as well as between DNA and DNA/PM (D) are shown (* p<0.05, ** p<0.001,*** p<0.001).