Table 3.

Cross-Sectional Multivariate Linear Regression Association of Cognitive Function between Diuretic Users compared to No Antihypertensive Medication and Other Antihypertensive Medication Users

	N	3MS		TMT-A		TMT-B		CVLT-FRS		CVLT-FRL		CVLT-Sum		RO-IR		RO-DR		RO_Copy
		β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE
Diuretic vs. C	459	.028	.26	.017	.98	.043	2.51	.048*	.18	.048*	.18	.057**	.57	−.002	.25	−.019	.25	.033	.17
Diuretic vs. O		.026	.30	.021	1.17	.036	3.09	.053	.21	.076*	.21	.104***	.64	.021	.28	−.013	.28	.025	.19
Loop vs. C	111	−.052	.50	.007	1.81	.046	4.62	−.002	.34	.030	.34	.002	1.10	−.028	.47	−.051	.47	.016	.31
Loop vs. O		−.076	.53	.021	1.94	.047	5.17	−.012	.36	−.026	.36	.026	1.11	−.036	.47	−.087*	.47	.014	.31
Thiazide vs C	165	.023	.38	.018	1.40	.046	3.59	.017	.26	−.004	.26	.028	.84	−.002	.36	−.015	.36	.011	.24
Thiazide vs. O		.019	.42	.032	1.59	.051	4.24	.021	.28	.011	.29	.065	.89	.019	.39	−.019	.38	−.004	.26
Ksparing vs. C	192	.041	.36	.015	1.30	.014	3.43	.068**	.25	.094***	.25	.067**	.81	.006	.35	.004	.35	.026	.23
Ksparing vs. O		.049	.40	.007	1.44	−.004	4.05	.080**	.28	.153***	.28	.126***	.85	.024	.36	.015	.36	.018	.25
KNsparing vs. C	267	−.001	.32	.013	1.21	.054*	3.01	.010	.22	−.017	.22	.023	.71	−.010	.31	−.034	.31	.025	.20
KNsparing vs. O		−.011	.36	.032	1.41	.057	3.62	.011	.24	−.006	.24	.059	.76	−.008	.34	−.046	.33	.017	.22

β=beta coefficient, SE=standard error

3MS = Modified Mini Mental State Exam; TMT-A = Trail Making Test, Part A; TMT-B = Trail Making Test, Part B; CVLT = California Verbal Learning Test (CVLT-FRS = short delayed free recall; CVLT-FRL = long delayed free recall; CVLT-Sum = Sum of trials 1 to 5 of List A); RO = Modified Rey-Osterrieth Complex Figure Test (RO-IR = immediate recall; RO-DR = delayed recall; RO-Copy = Copy). C = No antihypertensive medication use; O = Other antihypertensive medication use (calcium channel blockers, beta blockers, others).

^*P < 0.05,

^**P<0.01,

^***P<0.001.