Table 4.

Cross-Sectional Multivariate Linear Regression Association of Cognitive Function between ACE-I and AT2RB Users Compared to No Antihypertensive Medication or Other Antihypertensive Medication Users

	N	3MS		TMT-A		TMT-B		CVLT-FRS		CVLT-FRL		CVLT-Sum		RO-IR		RO-DR		RO_Copy
		β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE
ACE-I vs. C	309	−.014	.31	.001	1.1	−.007	2.9	.018	.21	.011	.21	.001	.69	−.020	.30	−.012	.30	−.040	.20
ACE-I vs. O		−.020	.33	−.009	1.2	−.025	3.2	.029	.23	.034	.23	.009	.72	.009	.31	.004	.31	−.013	.21
ACE-I BBBC vs. C	207	−.007	.36	.005	1.3	−.011	3.3	.004	.25	.002	.25	−.011	.81	−.028	.35	−.023	.35	−.015	.23
ACE-I BBBC vs. O		.011	.38	−.002	1.3	−.023	3.7	.009	.26	.021	.27	−.010	.82	−.002	.35	−.009	.36	−.021	.23
ACE-I BBBNC vs C	102	−.015	.49	−.008	1.7	−.004	4.5	.031	.33	.016	.33	.022	1.1	−.001	.47	.008	.46	.012	.30
ACE-I BBBNC vs. O		−.026	.51	−.016	1.8	−.019	5.0	.039	.35	.038	.35	.034	1.1	.017	.46	.021	.45	.009	.30
AT2RB vs. C	61	−.027	.62	−.009	2.2	−.001	5.7	.026	.42	.028	.42	.016	1.4	−.011	.59	.008	.59	.004	.38
AT2RB vs. O		−.063	.64	−.020	2.3	−.014	6.3	.024	.43	.036	.44	.016	1.4	−.019	.58	−.006	.57	−.029	.38

β =beta coefficient, SE=standard error

3MS = Modified Mini Mental State Exam; TMT-A = Trail Making Test, Part A; TMT-B = Trail Making Test, Part B; CVLT = California Verbal Learning Test (CVLT-FRS = short delayed free recall; CVLT-FRL = long delayed free recall; CVLT-Sum = Sum of trials 1 to 5 of List A); RO = Modified Rey-Osterrieth Complex Figure Test (RO-IR = immediate recall; RO-DR = delayed recall; RO-Copy = Copy).

C = No antihypertensive medication use; O = Other antihypertensive medication use (calcium channel blockers, beta blockers, others).