Table 3.

Regional information of decreased grey matter density (cluster size >100 voxels) in patients with COPD compared with healthy controls

Area	Volume (mm3)	Brodmann areas	MNI coordinate			t-score (peak)
			x	y	z
Rectus_R	118	11	9	39	−20	4.31
Precentral_L	100	6	−51	−5	33	4.95
Cingulum_Ant_R	485	32	8	38	17	5.88
Cingulum_Ant_L	212	32	−8	38	18	4.49
Cingulum_Mid_R	157	24	6	−9	42	4.87
Cingulum_Mid_L	136	24	−6	−9	41	4.91
Temporal_Sup_ L	280	22/42	−60	−33	3	4.99
Temporal_Sup/Rolandic_Oper _L	837	22	−57	−14	10	4.91
Insula/Temporal_Sup/Rolandic_Oper _R	2821	13/22/47	44	11	−5	5.15
Insula/Temporal_Sup/Rolandic_Oper _L	1551	13/22/47	−33	12	−15	4.48
Thalamus/pulvinar_L	1270		−12	−30	3	6.46
Thalamus/pulvinar_R	2210		12	−26	8	5.29
Caudate_L	212		−9	14	14	4.19

COPD, chronic obstructive pulmonary disease.