Table 6.
Cytoskeletal proteins in Ich, T.thermophila and H. sapiens
| Protein type | Ich | T. thermophila | H. sapiens |
|---|---|---|---|
| Tubulins and modifying enzymes | |||
| α-Tubulin | 1 | 1 | 9 |
| α-Tubulin-like | 0 | 3 | 0 |
| β-Tubulin | 3 | 2 | 9 |
| β-Tubulin-like | 0 | 6 | 0 |
| γ-Tubulin | 1 | 1 | 2 |
| ε-Tubulin | 1 | 1 | 1 |
| δ-Tubulin | 0 | 1 | 1 |
| η-Tubulin | 1 | 1 | 0 |
| ι-Tubulin | 0 | 3 | 0 |
| Tubulin tyrosine ligase-like | 31 | 50 | 14 |
| Motor proteins | |||
| Kinesin motor domain | 41 | 78 | 48 |
| Dynein heavy chain | 19 | 25 | 16 |
| Dynein intermediate chain | 6 | 6 | 7 |
| Dynein light intermediate chain | 1 | 2 | 3 |
| Dynein light chain | 16 | 14 | 9 |
| Myosin motor domain | 3 | 13 | 22 |
| Centrins | |||
| Centrin 1 | 1 | 1 | 1 |
| Centrin 2 | 2 | 1 | 1 |
| Centrin 3 | 1 | 1 | 1 |
| Centrin 4 | 1 | 1 | 0 |
| Core basal body proteins (also includes centrins 2, 3; δ-, ε-tubulins) | |||
| Bld10/Cep135 | 1 | 1 | 1 |
| Centriolin | 0 | 1 | 1 |
| Cep76 | 0 | 0 | 1 |
| Cep164 | 0 | 1 | 1 |
| Dip13 | 0 | 0 | 2 |
| Poc1 | 1 | 1 | 2 |
| Poc5 | 1 | 1 | 1 |
| Sas4/CPAP | 2 | 1 | 2 |
| Sas6 | 1 | 2 | 1 |
| VFL1a/CLERC | 1 | 2 | 1 |
| WDR16 | 1 | 1 | 1 |
| Ciliopathy associated proteins | |||
| MKS1 | 1 | 1 | 1 |
| MKS3 | 2 | 2 | 1 |
| MKS4/Cep290 | 0 | 0 | 1 |
| MKS5/RPGRIP1L | 1 | 1 | 1 |
| MKS6/CCD2A | 1 | 1 | 1 |
| AHI1 | 1 | 1 | 1 |
| NPHP1 | 1 | 1 | 1 |
| NPHP3 | 0 | 0 | 1 |
| NPHP4 | 1 | 1 | 1 |
| BBS1 | 1 | 1 | 2 |
| BBS2, 5, 7, 8, or 9 | 1 | 1 | 1 |
| BBS3/ARL6 | 0 | 1 | 1 |
| BBS4 | 0 | 1 | 1 |