Fig 1.

(A) A total of 215 patients were epidermal growth factor receptor (EGFR) fluorescent in situ hybridization (FISH) negative (57.2%), and 161 were EGFR FISH positive (42.8%), including 122 with EGFR high polysomy (32.4%) and 39 with EGFR gene amplification (10.4%). Median survival was 48.3 months for the low polysomic group, 40.7 months for high polysomic, and 30.7 months for patients with gene amplification. (B) Patients with high polysomy or gene amplification (EGFR FISH+) had a median survival of 40.7 months, while patients with low polysomy (EGFR FISH−) had a median survival of 48.3 months. The difference was not statistically significant (P = .4).