Table 2.

Omnibus amino acid tests for ulcerative colitis versus control. Amino acid positions with omnibus P < 5 × 10⁻⁸ are shown.

HLA amino acid position	Codon middle nucleotide position (chromosome 6, NCBI36/hg18)	Degrees of freedom	Omnibus P value
HLA-DRβ1, amino acid 181	32,657,335	1	7.48 × 10−9
HLA-DRβ1, amino acid 104	32,657,566	1	4.70 × 10−12
HLA-DRβ1, amino acid 98	32,657,584	1	4.68 × 10−12
HLA-DRβ1, amino acid 37	32,660,037	4	1.46 × 10−8
HLA-DRβ1, amino acid 30	32,660,058	5	6.01 × 10−10
HLA-DRβ1, amino acid 13	32,660,109	5	1.39 × 10−10
HLA-DRβ1, amino acid 11	32,660,115	5	2.68 × 10−13
HLA-DQα1, amino acid 47	32,717,191	3	2.73 × 10−10
HLA-DQα1, amino acid 50	32,717,200	2	2.95 × 10−11
HLA-DQα1, amino acid 53	32,717,209	2	2.12 × 10−11
HLA-DQα1, amino acid 175	32,717,988	2	2.28 × 10−10
HLA-DQα1, amino acid 215	32,718,464	1	5.95 × 10−12
HLA-DQβ1, amino acid 185	32,737,733	1	8.62 × 10−11