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. 2012 Mar 27;106(9):1564–1570. doi: 10.1038/bjc.2012.101

Table 2. Aspirin or NSAIDs use and patient and tumour characteristics.

  Aspirin or NSAIDs use  
  None Prediagnosis and postdiagnosis Only postdiagnosis P -value
Colon cancer
 Sex
  Male 389 (52.0) 707 (53.8) 383 (52.5) 0.02
  Female 359 (48.0) 608 (46.2) 347 (47.5)  
         
 Age
  <65 years 237 (31.7) 451 (34.3) 292 (40.0) <0.001
  65–74 years 215 (28.7) 421 (32.0) 246 (33.7)  
  ⩾75 years 296 (39.6) 443 (33.7) 192 (26.3)  
         
 Grade
  I 87 (11.6) 176 (13.4) 96 (13.2) <0.001
  II 436 (58.3) 772 (58.7) 443 (60.7)  
  III 127 (17.0) 229 (17.4) 116 (15.9)  
  Unknown 98 (13.1) 138 (10.5) 75 (10.3)  
         
 Stage
  I 111 (14.8) 225 (17.1) 131 (17.9) <0.001
  II 274 (36.6) 476 (36.2) 271 (37.1)  
  III 170 (22.7) 359 (27.3) 201 (27.5)  
  IV 150 (20.1) 208 (15.8) 109 (14.9)  
  Unknown 43 (5.7) 47 (3.6) 18 (2.5)  
         
Rectal cancer
 Sex
  Male 284 (66.4) 460 (59.7) 311 (63.6) 0.1
  Female 144 (33.6) 311 (40.3) 178 (36.4)  
         
 Age
  <65 years 170 (39.7) 334 (43.3) 261 (53.4) <0.001
  65–74 years 125 (29.2) 252 (32.7) 148 (30.3)  
  ⩾75 years 133 (31.1) 185 (23.0) 80 (16.3)  
         
 Grade
  I 37 (8.6) 72 (9.3) 34 (6.9) 0.002
  II 240 (56.1) 401 (52.0) 288 (58.9)  
  III 46 (10.8) 87 (11.3) 77 (15.8)  
  Unknown 105 (24.5) 211 (27.4) 90 (18.4)  
         
 Stage
  I 112 (26.2) 252 (32.7) 147 (30.1) 0.1
  II 106 (24.8) 176 (22.8) 116 (23.7)  
  III 111 (25.9) 185 (24.0) 137 (28.0)  
  IV 70 (16.4) 117 (15.2) 68 (13.9)  
  Unknown 29 (6.8) 41 (5.3) 21 (4.3)  

Abbreviation: NSAID=non-steroid anti-inflammatory drug.