Table 2.
Complex | Switch I | Switch II | |||||
---|---|---|---|---|---|---|---|
Ras protein | Binding Partner | Mobile? | Prediction | Interface? | Mobile? | Prediction | Interface? |
H-Ras | Ras GAP | Yes | Correct | Yes | Yes | Correct | Yes |
H-Ras | PIP3 Kinase | No | Correct | Yes | Yes | Correct | Yes |
Rac | p67 Phox | Yes | Correct | Yes | No | Correct | No |
Rac | Pseudomonas toxin GAP domain | Yes | Correct | Yes | No | Correct | Yes |
Rac | Arfaptin | Yes | Correct | Yes | No | Correct | No |
Ran | RCC1 | Not a loop | N/A | No | Yes | Correct | Yes |
Ran | Nuclear transport factor 2 | Not a loop | N/A | No | No | Incorrect | No |
CDC42 | CDC42 GAP | Yes | Correct | Yes | No | Correct | Yes |