Table 2.
Example showing how a high-resolution DR–DQ haplotype shows differences in class II eplet loads among serologically defined DR antigen mismatches (Adapted from Duquesnoy, 2008a).
| RECIPIENT | |||||||||
| DR11: | DRB1*11:01 | DRB3*02:01 | DQB1*03:01 | DQA1*05:01 | |||||
| DR16: | DRB1*16:01 | DRB5*02:02 | DQB1*05:02 | DQA1*01:02 | Eplet | DRB1 | DRB3/4/5 | DQB1 | DQA1 |
| Donor | Total | Eplets | Eplets | Eplets | Eplets | ||||
| DR1 | DRB1*01:01 | None | DQB1*05:01 | DQA1*01:01 | 12 | 8 | 0 | 2 | 2 |
| DR4 | DRB1*04:01 | DRB4*01:01 | DQB1*03:01 | DQA1*03:02 | 16 | 3 | 8 | 0 | 5 |
| DR7 | DRB1*07:01 | DRB4*01:01 | DQB1*02:02 | DQA1*02:01 | 28 | 7 | 8 | 7 | 6 |
| DR8 | DRB1*08:01 | None | DQB1*04:02 | DQA1*04:01 | 12 | 4 | 0 | 5 | 3 |
| DR9 | DRB1*09:01 | DRB4*01:01 | DQB1*03:03 | DQA1*03:02 | 27 | 11 | 8 | 3 | 5 |
| DR10 | DRB1*10:01 | None | DQB1*05:01 | DQA1*01:01 | 12 | 8 | 0 | 2 | 2 |
| DR11 | DRB1*11:01 | DRB3*02:02 | DQB1*03:01 | DQA1*05:01 | 0 | 0 | 0 | 0 | 0 |
| DR12 | DRB1*12:01 | DRB3*02:02 | DQB1*03:01 | DQA1*05:01 | 6 | 6 | 0 | 0 | 0 |
| DR13 | DRB1*13:01 | DRB3*01:01 | DQB1*06:03 | DQA1*01:03 | 20 | 3 | 7 | 8 | 2 |
| DR14 | DRB1*14:01 | DRB3*02:02 | DQB1*05:03 | DQA1*01:04 | 13 | 8 | 0 | 2 | 3 |
| DR15 | DRB1*15:01 | DRB5*01:01 | DQB1*06:02 | DQA1*01:02 | 9 | 0 | 2 | 7 | 0 |
| DR16 | DRB1*16:02 | DRB3*02:02 | DQB1*03:01 | DQA1*05:01 | 2 | 2 | 0 | 0 | 0 |
| DR17 | DRB1*03:01 | DRB3*01:01 | DQB1*02:01 | DQA1*05:01 | 19 | 5 | 7 | 7 | 0 |
| DR18 | DRB1*03:02 | DRB3*01:01 | DQB1*04:02 | DQA1*04:01 | 18 | 3 | 7 | 5 | 3 |