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DHA bioactive metabolome. DHA is the precursor to D-series resolvin (RvD), aspirin-triggered resolvin D (AT-RvD), maresins (MaR), protectin D1 (PD1), and aspirin-triggered protectin D1 (AT-PD1). Another metabolic fate of DHA is conversion to docosahexaenoyl ethanolamide (DHEA). See text for details on the recently identified novel series of bioactive oxygenated DHEA-derived products including 15-HEDPEA and 10,17S-diHDHEA.
