Skip to main content
. 2012 Apr 17;3:81. doi: 10.3389/fimmu.2012.00081

Table 1.

Key structures of the SPM: resolvins, protectins, and maresins.

RvE1 Resolvin E1 (5S,12R,18R-trihydroxy-eicosa-6Z,8E,10E,14Z,16E-pentaenoic acid)
RvE2 Resolvin E2 (5S,18R-dihydroxy-eicosapentaenoic acid)
PD1/NPD1 Protectin D1/neuroprotectin D1 (10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid)
RvD1 Resolvin D1 (7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid)
RvD2 Resolvin D2 (7S,16R,17S-trihydroxydocosa-4Z,8E,10Z,12E,14E,19Z-hexaenoic acid)
RvD3 Resolvin D3 (4S,11,17S-trihydroxydocosa-5,7E,9E,13Z,15E,19Z-hexaenoic acid)
RvD4 Resolvin D4 (4S,5,17S-trihydroxydocosa-6E,8E,10Z,13Z,15E,19Z-hexaenoic acid)
RvD5 Resolvin D5 (7S,17S-dihydroxy-docosa-4Z,8E,10Z,13Z,15E,19Z-hexaenoic acid)
MaR1 Maresin 1 (7,14-dihydroxy-docosa-4Z,8,10,12,16Z,19Z-hexaenoic acid)

Complete structures of the key SPM are reported and total organic synthesis was recently reviewed in Serhan and Petasis (2011).

HHS Vulnerability Disclosure