Table 1.
EpCAM and Trop2 overexpression in relation to clinicopathologic factors in adenocarcinoma
| Parameter | Number | EpCAM overexpression | P value | Trop2 overexpression | P value |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 52 | 26 (50.0) | 0.019 | 13 (25.0) | 0.621 |
| Female | 48 | 13 (27.1) | 10 (20.8) | ||
| Age at diagnosis | 100 | 0.490 | 0.102 | ||
| Histologic grade | |||||
| Well differentiated | 42 | 7 (16.7) | 0.000 | 5 (11.9) | 0.015 |
| Moderately differentiated | 38 | 15 (39.5) | 9 (23.7) | ||
| Poorly differentiated | 20 | 17 (85.0) | 9 (45.0) | ||
| T stage | |||||
| pT1 | 68 | 21 (30.9) | 0.015 | 21 (24.7) | 0.335 |
| pT2, 3, 4 | 32 | 18 (56.3) | 2 (13.3) | ||
| N stage | |||||
| pN0 | 80 | 27 (33.8) | 0.031 | 17 (21.3) | 0.406 |
| pN1, 2, 3 | 20 | 12 (60.0) | 6 (30.0) | ||
| TNM stage | |||||
| I | 68 | 21 (30.9) | 0.050 | 15 (22.1) | 0.70 |
| II, III | 32 | 18 (56.3) | 8 (25.0) | ||
| Smoking | 81 | ||||
| Never | 39 | 11 (28.2) | 0.085 | 7 (17.9) | 0.947 |
| Quit | 19 | 7 (36.8) | 4 (21.1) | ||
| Current | 23 | 13 (56.5) | 4 (17.4) | ||
| Smoking (PY) | 79 | 0.376 | 0.441 | ||