Table 2.
Descriptive statistics of the mean value and its standard deviation as well as the median values prior and after treatment of rhabdoid tumor xenografts with vehicle (DMSO), suberoylanilide hydroxamic acid (SAHA), irradiation (XRT) or XRT and SAHA
| Parameter | Control | SAHA | XRT | SAHA + XRT | ||||
|---|---|---|---|---|---|---|---|---|
| Mean (SD) prior | Mean (SD) after | Mean (SD) prior | Mean (SD) after | Mean (SD) prior | Mean (SD) after | Mean (SD) prior | Mean (SD) after | |
| k1 | 0.015 (0.04) | 0.13 (0.06) | 0.16 (0.04) | 0.1 (0.01) | 0.14 (0.01) | 0.16 (0.02) | 0.14 (0.01) | 0.15 (0.05) |
| k2 | 0.32 (0.07) | 0.38 (0.02) | 0.37 (0.12) | 0.24 (0.08) | 0.33 (0.03) | 0.34 (0.02) | 0.39 (0.03) | 0.39 (0.02) |
| k3 | 0.08 (0.03) | 0.11 (0.06) | 0.07 (0.04) | 0.1 (0.08) | 0.06 (0.02) | 0.08 (0.02) | 0.08 (0.01) | 0.09 (0.00) |
| VB | 0.01 (0.001) | 0.02 (0.002) | 0.03 (0.002) | 0.01 (0.001) | 0.04 (0.001) | 0.01 (0.001) | 0.04 (0.003) | 0.01 (0.001) |
| Influx constant Ki (=(k1xk3)/(k2+k3) | 0.03 | 0.03 | 0.02 | 0.03 | 0.02 | 0.03 | 0.02 | 0.03 |
| Max mSUV | 1323 (368) | 1593 (631) | 2341 (1135) | 729 (305) | 1676 (782) | 1578 (1206) | 1314 (767) | 1158 (816) |