Table 3. CpG methylation in the INS promoter in T2D patients and controls.
T2D Patients (N = 132) | T2D CONTROLS (N = 186) | ||
DNA methylation (%) | p | ||
CpG -19 | 47±11 | 54±10 | 2.10−6 |
CpG -69 | 88±11 | 88±6 | 0.22 |
CpG -102 | 68±18 | 64±13 | 0.01 |
CpG -135 | 58±10 | 55±10 | 0.06 |
CpG -180 | 57±19 | 61±11 | 0.14 |
CpG -206 | 91±10 | 93±7 | 0.79 |
CpG -234 | 57±9 | 51±6 | 5.10−8 |
Results are expressed as mean ± sd. P-values are calculated by Wilcoxon rank sum test.