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. 2012 Apr 10;3(5):911–919. doi: 10.1364/BOE.3.000911

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©2012 Optical Society of America

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.

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Fig. 2 — Experimental setup of rat SV-OCT. Panel A shows an overview of the imaging station with the male Wistar rat pinned to the imaging breadboard. Panel B shows a close up of the pin fixation. The animal is resting on a heated gel pack to maintain 37°C body temperature (panel B). The animal underwent tracheotomy and is receiving inhalational anesthetic. Breath-hold was conducted to reduce bulk motion from >40μm in the anterior-posterior direction to <8μm (panel C). A close up of the exposed spinal cord is shown in panel D. Panel E demonstrates structural OCT data. Panel F shows an en face projection of the SV-OCT data. A histology specimen is provided in panel G for comparison, with the dorsal vein (1) marked.