Table 2. Genotype/phenotype correlations for the patients with (D) and without (N) 35delG mutation.
SNHL degree | Patients analyzed | DD | DN | NN | %DD/%NN |
moderate | 18 | 3 | 2 | 13 | 16.7/72.2** |
moderate/severe | 23 | 7 | 1 | 15 | 30.4/65.2 |
severe | 88 | 36 | 11 | 41 | 40.9/46.6 |
severe/profound | 45 | 27 | 7 | 11 | 60.0/24.4 |
profound | 217 | 105 | 30 | 82 | 48.4/37.8 |
Total | 391 | 178 | 51 | 162 | 45.5/41.4 |
The difference of DD % with other patient groups is significant (P<0,02).