Table 3. Biological markers associated to increased coronary artery calcifications after adjustment for age, gender, diabetes mellitus and smoking (the p-value of the test for trend is given).
| Coronary artery calcifications | Coronary artery calcifications | ||||||||
| <100 (n = 79) | [100–400[ (n = 50) | ≥400 (n = 66) | [100–400[ vs <100 | ≥400 vs <100 | |||||
| Variable | n | % | n | % | n | % | Global P-value | OR [CI 95%] | OR [CI 95%] |
| Hemoglobin (g/dL) | |||||||||
| <12.5 | 23 | 29.11 | 16 | 32.65 | 22 | 33.85 | 0.49 | 1 | 1 |
| [12.5–13.8[ | 27 | 34.18 | 18 | 36.73 | 20 | 30.77 | 0.53 [0.17;1.61] | 0.37 [0.12;1.16] | |
| ≥13.8 | 29 | 36.71 | 15 | 30.61 | 23 | 35.38 | 0.50 [0.16;1.61] | 0.52 [0.17;1.62] | |
| Serum creatinine (µmol/L) | |||||||||
| <137 | 32 | 40.51 | 18 | 36.00 | 14 | 21.21 | 0.25 | 1 | 1 |
| [137–190[ | 26 | 32.91 | 14 | 28.00 | 24 | 36.36 | 0.77 [0.27;2.22] | 1.59 [0.55;4.55] | |
| ≥190 | 21 | 26.58 | 18 | 36.00 | 28 | 42.42 | 1.76 [0.61;5.13] | 3.17 [1.07;9.37] | |
| Calcium (mmol/L) | |||||||||
| <2.32 | 25 | 31.65 | 22 | 44.00 | 20 | 30.30 | 0.34 | 1 | 1 |
| [2.32–2.44[ | 32 | 40.51 | 11 | 22.00 | 19 | 28.79 | 0.53 [0.18;1.53] | 1.04 [0.36;2.97] | |
| ≥2.44 | 22 | 27.85 | 17 | 34.00 | 27 | 40.91 | 1.16 [0.41;3.32] | 2.08 [0.72;6.04] | |
| Phosphate (mmol/L) | |||||||||
| <0.97 | 23 | 29.11 | 21 | 42.00 | 19 | 28.79 | 0.46 | 1 | 1 |
| [0.97–1.16[ | 28 | 35.44 | 18 | 36.00 | 23 | 34.85 | 0.95 [0.35;2.58] | 1.30 [0.47;3.64] | |
| ≥1.16 | 28 | 35.44 | 11 | 22.00 | 24 | 36.36 | 0.54 [0.17;1.74] | 1.44 [0.46;4.45] | |
| FEPO4 (%) | |||||||||
| <25.86 | 33 | 43.42 | 14 | 31.11 | 13 | 22.03 | 0.01 | 1 | 1 |
| [25.86–38.71[ | 24 | 31.58 | 19 | 42.22 | 17 | 28.81 | 2.95 [1.01;8.64] | 2.66 [0.86;8.21] | |
| ≥38.71 | 19 | 25.00 | 12 | 26.67 | 29 | 49.15 | 2.15 [0.67;6.95] | 5.47 [1.76;17.0] | |
| 1.25 (OH)2 vitamin D (pg/mL) | |||||||||
| <23 | 23 | 29.11 | 18 | 36.00 | 18 | 27.27 | 0.20 | 1 | 1 |
| [23–38[ | 27 | 34.18 | 15 | 30.00 | 23 | 34.85 | 0.23 [0.07;0.79] | 0.30 [0.09;1.03] | |
| ≥38 | 29 | 36.71 | 17 | 34.00 | 25 | 37.88 | 0.33 [0.10;1.05] | 0.45 [0.14;1.44] | |
| 25(OH) vitamin D (ng/mL) | |||||||||
| <15.7 | 24 | 32.00 | 19 | 38.00 | 20 | 30.77 | 0.94 | 1 | 1 |
| [15.7–25.0[ | 23 | 30.67 | 15 | 30.00 | 24 | 36.92 | 1.13 [0.39;3.26] | 1.53 [0.54;4.40] | |
| ≥25.0 | 28 | 37.33 | 16 | 32.00 | 21 | 32.31 | 1.01 [0.36;2.89] | 1.22 [0.42;3.49] | |
| Intact PTH (pg/mL) | |||||||||
| <36 | 32 | 40.51 | 15 | 30.00 | 16 | 24.24 | 0.35 | 1 | 1 |
| [36–75[ | 26 | 32.91 | 20 | 40.00 | 20 | 30.30 | 1.40 [0.50;3.94] | 1.11 [0.38;3.24] | |
| ≥75 | 21 | 26.58 | 15 | 30.00 | 30 | 45.45 | 1.15 [0.39;3.36] | 2.10 [0.74;5.97] | |
| FGF 23 (RU/mL) | |||||||||
| <173.30 | 58 | 73.42 | 36 | 72.00 | 35 | 53.03 | 0.003 | 1 | 1 |
| ≥173.30 | 21 | 26.58 | 14 | 28.00 | 31 | 46.97 | 2.05 [0.71;5.92] | 5.40 [1.91;15.3] | |
| Osteoprotegerin (pmol/L) | |||||||||
| <10.71 | 65 | 82.28 | 27 | 54.00 | 37 | 56.06 | 0.11 | 1 | 1 |
| ≥10.71 | 14 | 17.72 | 23 | 46.00 | 29 | 43.94 | 2.73 [1.03;7.26] | 2.41 [0.91;6.39] | |