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. 2012 May 2;7(5):e36623. doi: 10.1371/journal.pone.0036623

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Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Schematic showing the location of putative transmembrane domains (TMDs) and conserved structural domains identified using the Conserved Domains Database (NCBI), including: MIR (Mannosyltransferase, IP₃R and RyR) domains (pfam02815), RIH (RyR and IP₃R Homology) domains (pfam01365), SPRY (SPla and the RyR) domains (pfam00622), RyR domains (RyR repeated domain) (pfam02026), RIH-associated domains (RyR and IP₃R Homology associated) (pfam08454), EF hands, and suppressor-domain-like domains (SD) (pfam08709).