Table 1.
Mouse |
Human |
||||
---|---|---|---|---|---|
Embryonic LTi | Postnatal LTi | Embryonic LTi | Postnatal LTi | ||
Th17 gene | IL-22 | + | + | + | + |
IL-17A | + | + | + | Low | |
IL-23R | + | + | + | + | |
Transcription | RORγt | + | + | + | + |
Factor | ID2 | + | + | + | + |
AHR | + | + | + | + | |
Surface | CD3 | − | − | − | − |
Marker | CD4 | +/− | +/− | − | − (Low) |
CD117 | + | + | + | + | |
IL-7Rα (CD127) | + | + | + | + | |
IL-2Rα (CD25) | + | + | + | + | |
TNFSF | OX40L (TNFSF4) | − | +++ | − | +++ |
CD30L (TNFSF8) | − | + | − | − | |
TRANCE (TNFSF11) | + | + | + | + | |
TNF, LTα, LTβ | ++ | ++ | ++ | ++ | |
DR3 (TNFRSF25) | + | + | + | + | |
Chemokine | CXCR5 | + | + | + | + |
Receptor | CCR7 | + | + | + | + |
CCR6 | + | + | + | + |