Figure 3.

Shortened duration of vaginal gonococcal infection in IL-22-ko mice. IL-22-ko or WT C57BL/6 mice (10 per group) were infected vaginally with N. gonorrhoeae on day 0; infection was monitored by vaginal swab culture, and the neutrophil influx was determined by microscopic examination of vaginal smears. (A) Number of recoverable N. gonorrhoeae (mean ± SD, CFU/mouse); (B), percentage of mice remaining infected each day (P < 0.001; Kaplan–Meier); (C), neutrophils relative to epithelial cells (mean ± SD, %). Data shown from one of three experiments yielding similar results.