Table 3.
Eucapnic Voluntary Hyperpnea in Women at 40 and 60L/min and in Men at 60 and 90L/min
RPB (0-10) |
(L/min) |
(% pred peak) |
(L/min) |
(L/min) |
VT (% FVC) |
Fb (bpm) |
PETCO2 (torr) |
(%) |
EELV (% TLC) |
HR (% pred peak) |
|
---|---|---|---|---|---|---|---|---|---|---|---|
Women @ rest |
1 ± 1 | 0.21 ± 0.02 | 10 ± 1 | 0.17 ± 0.02 | 8 ± 1 | 21 ± 7 | 12 ± 4 | 37 ± 3 | 7 ± 2 | 55 ± 7 | 42 ± 8 |
Men @ rest |
0 ± 0 | 0.28 ± 0.03 | 8 ± 1 | 0.22 ± 0.04 | 10 ± 2 | 15 ± 3 | 12 ± 3 | 42 ± 2 | 6 ± 1 | 50 ± 7 | 38 ± 7 |
P value @ rest |
ns | < 0.0001 | 0.0062 | 0.0016 | 0.0262 | 0.0493 | ns | 0.0002 | 0.0159 | ns | ns |
Women @ 40 |
2 ± 2 | 0.24 ± 0.03 | 11 ± 2 | 0.19 ± 0.03 | 41 ± 2 | 37 ± 8 | 30 ± 0 | 35 ± 1 | 36 ± 7 | 54± 6 | 47 ± 8 |
Women @ 60 |
4 ± 3 | 0.28 ± 0.03 | 13 ± 2 | 0.18 ± 0.02 | 60 ± 1 | 46 ± 9 | 36 ± 0 | 40 ± 1 | 53 ± 9 | 50 ± 7 | 47 ± 7 |
Men @ 60 |
3 ± 1 | 0.34 ± 0.05 | 10 ± 1 | 0.24 ± 0.04 | 62 ± 1 | 31 ± 5 | 36 ± 0 | 41 ± 3 | 35 ± 4 | 43 ± 8 | 41 ± 7 |
P value @ 60 |
ns | 0.0023 | 0.0028 | 0.0009 | 0.0482 | 0.0004 | ns | ns | < 0.0001 | ns | ns |
Men @ 90 |
4 ± 1 | 0.38 ± 0.04 | 11 ± 1 | 0.32 ± 0.04 | 93 ± 2 | 43 ± 7 | 40 ± 0 | 40 ± 1 | 54 ± 6 | 44 ± 9 | 45 ± 7 |
Values are mean ± SD. RPB, rating of perceived breathlessness (Borg 0-10 scale); , oxygen uptake (expressed in L/min and as percent of predicted peak based on age and gender); , carbon dioxide production; , minute ventilation; VT, tidal volume (expressed as percent of FVC); Fb, breathing frequency (expressed in breaths per minute, bpm); PETCO2, end-tidal CO2; , ratio of minute ventilation to maximal voluntary ventilation predicted from FEV1 (PMVV=37.5*FEV1); EELV, end-expiratory lung volume (expressed as percent of TLC); HR, heart rate (expressed as percent of predicted peak heart rate based on age and gender); and ns, non-significant.