Table 2.

Summary of Drugs Administered to Experimental Baboons

Induction Therapy	Dose	Duration
Thymoglobulin	2.0–2.5mg/kg i.v.	Day -3 and -1
Methylprednisolone	5 mg/kg i.v.	Before each dose of ATG and on day 0 The dose was then reduced by 1 mg/kg/day, and discontinued on day 5
Maintenance Therapy	Dose	Duration
Anti-human CD154 mAb	20–25 mg/kg i.v.	Days −1, 0, 4, 7, 10, 14, then every 7 days (to maintain a trough level of 400–800 ng/ml)
Mycophenolate mofetil	20–150 mg/kg/d p.o. ×2 daily	From day -2 (to maintain a trough level of 3–6 ug/ml)
Supportive Therapy	Dose	Duration
Cefazolin	25mg/kg bid i.v.	For 3 days after surgery
Famotidine	0.25 mg/kg bid i.v.	From day -3 until day 14
Ganciclovir	5 mg/kg/ i.v.	From day -4 until day 21
Ketorolac	0.5 mg/kg i.v.	Before every dose of anti-CD154
Buprenorphine	0.01 mg/kg bid i.v.	For 3 days after surgery