Table 1.
General characteristics of the study populations.
| Variable | Costa Rica Study |
Nurses’ Health Study |
Health Professionals Follow-Up Study |
|||
|---|---|---|---|---|---|---|
| Cases (n = 878) | Controls (n = 878) | Cases (n = 403) | Controls (n = 797) | Cases (n = 435) | Controls (n = 860) | |
| Age, years | 58.2 ± 10.9 | 58.1 ± 11.0 | 60.2 ± 6.3 | 59.6 ± 6.5 | 64.5 ± 8.6 | 64.2 ± 8.6 |
| % Female | 26 | 26 | 100 | 100 | 0 | 0 |
| % History of hypertension | 39 | 32 | 50 | 27 | 37 | 29 |
| % History of hypercholesterolemia | 31 | 29 | 53 | 41 | 49 | 40 |
| % History of diabetes | 23 | 15 | 15 | 6 | 9 | 4 |
| % Current smokers | 38 | 21 | 27 | 25 | 10 | 9 |
| BMI, kg/m2 | 26.0 ± 4.0 | 26.5 ± 4.3 | 26.6 ± 5.4 | 25.1 ± 4.3 | 26.0 ± 3.2 | 25.6 ± 3.3 |
| DIETARY INTAKE OF FATTY ACIDS, g | ||||||
| Alpha-linolenic | 1.71 ± 0.86 | 1.61 ± 0.77 | – | – | – | – |
| Linoleic | 19.1 ± 9.6 | 17.9 ± 7.9 | – | – | – | – |
| ADIPOSE TISSUE FATTY ACIDS, % TOTAL | ||||||
| Alpha-linolenic | 0.64 ± 0.21 | 0.68 ± 0.21 | – | – | – | – |
| Linoleic | 15.4 ± 3.7 | 16.0 ± 3.8 | – | – | – | – |
| MINOR ALLELE FREQUENCY, % | ||||||
| rs174556 (C/T) | 45 | 45 | 31 | 28 | 30 | 29 |
| rs3834458 (T/deletion) | 48 | 48 | – | – | – | – |
| rs174570 (C/T) | 37 | 39 | 13 | 13 | 13 | 14 |
| rs2524299 (A/T) | 28 | 26 | 12 | 11 | 11 | 13 |
| rs174589 (G/C) | 30 | 29 | 22 | 21 | 20 | 20 |
| rs174627(C/T) | 12 | 11 | 18 | 19 | 17 | 17 |