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. 2012 May;5(3):199–207. doi: 10.1177/1756283X11430859

Figure 4.

Figure 4.

Liver biopsy in the setting of methotrexate. (A) The hepatocytes show macrovesicular steatosis, nuclear hyperchromasia, and anisonucleosis. (B) A trichrome stain shows bridging fibrosis and sinusoidal fibrosis extending from portal tracts.