Figure 4.

Liver biopsy in the setting of methotrexate. (A) The hepatocytes show macrovesicular steatosis, nuclear hyperchromasia, and anisonucleosis. (B) A trichrome stain shows bridging fibrosis and sinusoidal fibrosis extending from portal tracts.

Liver biopsy in the setting of methotrexate. (A) The hepatocytes show macrovesicular steatosis, nuclear hyperchromasia, and anisonucleosis. (B) A trichrome stain shows bridging fibrosis and sinusoidal fibrosis extending from portal tracts.