Figure 3. Crosstalk between trans-channel and transverse ionic pathways.

(a) The transverse current I_sens concurrently measured with I_ion under V_long = 0.5 V and V_trans = 0.5 V conditions. The background current is about 100 pA. Positive pulse-like signals were found instead of current blockades. (b) Direct comparison of the I_ion blockade and simultaneously detected I_sens spike. The line shapes of these curves are almost identical to each other though the sign is opposite. c, A current histogram built with the I_sens - t curve. The base level I₀ is subtracted from I_sens. Solid curves are Gaussian distributions centered at 36 pA and 73 pA.